Dr. Eng-Shiong Tan

Intervention Cardiologist

Dr. Tan is our Intervention Cardiologist, specialized in coronary interventions such as Transcatheter RF-ablation of arrhythmias.

Dr. Tan obtain his bachelor of medicine in 1978 from the University of Amsterdam. He obtained his master of medicine in 1980 and following on from this passed his Medical Qualifying Examination in 1983. In addition to this, he obtained a V.Q.E., qualifying him as a physician in the USA. Dr. Tan went on to specialize in cardiology, completing this in 1993. Additionally, he completed examinations on radiation for medical specialists in 1998, and NASPE: Examination of special competency-cardiac pacing and cardioversion defibrillation in 2001.

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Dr. Tan went on to complete a PhD thesis on: “Advanced clinical approaches in complex cardiovascular disease” in 2008. As well as completing the BROK course in December 2012.

Dr. Tan has work in numerous excellent hospitals in the Netherlands. His initial medical internship was conducted at the University Hospital of the University of Amsterdam from 1981-1983. He completed a residency of cardiac rehabilitation at RKO Hospital, in Amsterdam from 1985 until 1986. As well as a residency in internal medicine at RKZ Hospital in Beverwijk (affiliated with the Academic Hospital of the University of Amsterdam). His cardiology specialization was conducted at the Thorax Centre at the University of Groningen, and the Zuiderziekhuis Hospital in Rotterdam (affiliated with the thorax centre of the University of Rotterdam). In addition to this, he conducted his electrophysiology fellowship at the University Hospital in Maastricht.

Dr. Tan has previous clinic experience in pediatric cardiology conducting angiographic diagnostics and intervention, as well as echocardiography, transthoracic and transesophageal experience.

Dr. Tan currently works at the University Medical Center in Groningen in addition to working at the Marbella Lyme Clinic as an intervention cardiologist.

Publications:

Effect of Metformin on Left Ventricular Function After Acute Myocardial Infarction in Patients Without Diabetes: The GIPS-III Randomized Clinical Trial. Chris P H Lexis, Iwan C C van der Horst, Erik Lipsic, Wouter G Wieringa, Rudolf A de Boer, Ad F M van den Heuvel, Hindrik W van der Werf, Remco A J Schurer, Gabija Pundziute, Eng S Tan, […], Barbara H W Molmans, Anouk N A van der Horst-Schrivers, Bruce H R Wolffenbuttel, Gert J Ter Horst, Albert C van Rossum, Jan G P Tijssen, Hans L Hillege, Bart J G L de Smet, Pim van der Harst, Dirk J van Veldhuisen. JAMA The Journal of the American Medical Association 03/2014; DOI:10.1001/jama.2014.3315

The feasibility of optical coherence tomography guided thrombus aspiration in patients with non-ST-elevation myocardial infarction after initial conservative therapy – A pilot study Wouter G Wieringa, Chris P H Lexis, Gilles F H Diercks, Erik Lipsic, Eng-Shiong Tan, Remco A.J. Schurer, Hindrik W van der Werf, Ad F M van den Heuvel, Albert J H Suurmeijer, Felix Zijlstra, Bart J G L de Smet, Gabija Pundziute International journal of cardiology 08/2013; 168(5). DOI:10.1016/j.ijcard.2013.07.133

Operator dependence of outcome after primary percutaneous coronary intervention. Vlaar PJ, de Smet BJ, van den Heuvel AF, Anthonio RL, Jessurun GA, Tan ES, Hillege HL, Zijlstra F. Eurointervention, 2011 Jan;6(6):760-7.

Surgical vs. transcatheter pulmonary vein isolation as first invasive treatment in patients with atrial fibrillation: a matched group comparison Gijs E De Maat, Isabelle C Van Gelder, Michiel Rienstra, Anne-Floor B E Quast, Eng S Tan, Ans C P Wiesfeld, Alberto Pozzoli, Massimo A Mariani. EuroIntervention: journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 01/2011; 6(6):760-7. DOI:10.4244/EIJV6I6A129

Intracoronary versus intravenous administration of abciximab in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention with thrombus aspiration: the comparison of intracoronary versus intravenous abciximab administration during emergency reperfusion of ST-segment elevation myocardial infarction (CICERO) trial. Gu YL, Kampinga MA, Wieringa WG, Fokkema ML, Nijsten MW, Hillege HL, van den Heuvel AF, Tan ES, Pundziute G, van der Werf R, Hoseyni Guyomi S, van der Horst IC, Zijlstra F, de Smet BJ. Circulation. 2010 Dec 21;122(25):2709-17

Value and limitations of electromechanical endocardial mapping in the assessment of global and regional left ventricular function and transmural extent of infarction: a comparison with cardiovascular magnetic resonance van der Vleuten PA, Nijveldt R, Tan ES, Tio RA, van Rossum AC, Zijlstra F. Eurointervention, 2010 Nov;6(5):616-22.

Is the myocardial blush grade scored by the operator during primary percutaneous coronary intervention of prognostic value in patients with ST-elevation myocardial infarction in routine clinical practice? Kampinga MA, Nijsten MW, Gu YL, Dijk WA, de Smet BJ, van den Heuvel AF, Tan ES, Zijlstra F. Circ. Cardiovasc. Interv., 2010 Jun 1;3(3):216-23.

Evaluation of global left ventricular function assessment of non-fluorescent electromechanical endocardial mapping compared with biplane left ventricular contrast angiography. Tan ES, Van der Vleuten PA, Jessurun GA, Tio RA, Zijlstra F, Van Gelder IC. Neth Heart J. 2010 Feb;18(2):72-7

Effect of high-dose intracoronary adenosine administration during primary percutaneous coronary intervention in acute myocardial infarction: a randomized controlled trial. Fokkema ML, Vlaar PJ, Vogelzang M, Gu YL, Kampinga MA, de Smet BJ, Jessurun GA, Anthonio RL, van den Heuvel AF, Tan ES, Zijlstra F. Circ Cardiovasc Interv. 2009 Aug;2(4):323-9.

Pulmonary vein isolation of symptomatic refractory paroxysmal and persistent atrial fibrillation: A single centre and single operator experience in the Netherlands. Tan ES, Mulder BA, Rienstra M, Wiesfeld AC, Ahmed S, Zijlstra F, Van Gelder IC. Neth Heart J. 2009 Oct;17(10):366-72.

Feasibility and outcome of epicardial pulmonary vein isolation for lone atrial fibrillation using minimal invasive surgery and high intensity focused ultrasound. Klinkenberg TJ, Ahmed S, Ten Hagen A, Wiesfeld AC, Tan ES, Zijlstra F, Van Gelder IC. Europace. 2009 Dec;11(12):1624-31.

Intracoronary versus intravenous abciximab in ST-segment elevation myocardial infarction: rationale and design of the CICERO trial in patients undergoing primary percutaneous coronary intervention with thrombus aspiration. Gu YL, Fokkema ML, Kampinga MA, de Smet BJ, Tan ES, van den Heuvel AF, Zijlstra F. Trials. 2009 Sep 28;10:90

Electromechanical mapping of the left ventricle: possible tool for online decision making in the catheterization laboratory. Tan ES, Jessurun GA, Anthonio RL, Slart RH, Zijlstra F, Tio RA. J. Cardiovasc. Med. (Hagerstown). 2009 May;10(5):415-9

Differences between early, intermediate, and late angioplasty after coronary artery bypass grafting. Tan ES, Jessurun G, Deurholt W, van der Vleuten P, van den Heuvel A, Ebels T, Zijlstra F, Tio R. Crit Pathw Cardiol. 2008 Dec;7(4):239-44

The feasibility and safety of routine thrombus aspiration in patients with non-ST-elevation myocardial infarction. Vlaar PJ, Diercks GF, Svilaas T, Vogelzang M, de Smet BJ, van den Heuvel AF, Anthonio RL, Jessurun GA, Tan ES, Suurmeijer AJ, Zijlstra F. Catheter Cardiovasc Interv. 2008 Dec 1;72(7):937-42.

Cardiac death and reinfarction after 1 year in the Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS): a 1-year follow-up study. Vlaar PJ, Svilaas T, van der Horst IC, Diercks GF, Fokkema ML, de Smet BJ, van den Heuvel AF, Anthonio RL, Jessurun GA, Tan ES, Suurmeijer AJ, Zijlstra F. Lancet. 2008 Jun 7;371(9628):1915-20.

Closure of the femoral artery after cardiac catheterization: a comparison of Angio-Seal, StarClose, and manual compression. Deuling JH, Vermeulen RP, Anthonio RA, van den Heuvel AF, Jaarsma T, Jessurun G, de Smet BJ, Tan ES, Zijlstra F. Catheter Cardiovasc Interv. 2008 Mar 1;71(4):518-23.

Long-term outcome of the atrioventricular node ablation and pacemaker implantation for symptomatic refractory atrial fibrillation. Tan ES, Rienstra M, Wiesfeld AC, Schoonderwoerd BA, Hobbel HH, Van Gelder IC. Europace. 2008 Feb 12;

Thrombus aspiration during primary percutaneous coronary intervention. Svilaas T, Vlaar PJ, van der Horst IC, Diercks GF, de Smet BJ, van den Heuvel AF, Anthonio RL, Jessurun GA, Tan ES, Suurmeijer AJ, Zijlstra F. N Engl J Med. 2008 Feb 7;358(6):557-67.

The effect of electrical neurostimulation on collateral perfusion during acute coronary occlusion. de Vries J, Anthonio RL, Dejongste MJ, Jessurun GA, Tan ES, de Smet BJ, vanden Heuvel AF, Staal MJ, Zijlstra FBMC Cardiovasc Disord. 2007 Jun 27;7:18.

Incidence and angiographic predictors of collateral function in patients with stable coronary artery disease scheduled for percutaneous coronary intervention. de Vries J, Anthonio RL, van den Heuvel AF, Tan ES, Jessurun GA, de Smet BJ, DeJongste MJ, Zijlstra F. Catheter Cardiovasc Interv. 2007 Aug 1;70(2):197-202.

Persistent atrial fibrillation is associated with appropriate shocks and heart failure in patients with left ventricular dysfunction treated with an implantable cardioverter defibrillator.Rienstra M, Smit MD, Nieuwland W, Tan ES, Wiesfeld AC, Anthonio RL, Van den Berg MP, Van Veldhuisen DJ, Van Gelder IC. Am Heart J. 2007 Jan;153(1):120-6.

Right ventricular pacing and the risk of heart failure in implantable cardioverter-defibrillator patients. Smit MD, Van Dessel PF, Nieuwland W, Wiesfeld AC, Tan ES, Anthonio RL, Van Erven L, Van Veldhuisen DJ, Van Gelder IC. Heart Rhythm. 2006 ec;3(12):1397-403. Epub 2006 Aug 10.

Atrial fibrillation predicts appropriate shocks in primary prevention implantable cardioverter-defibrillator patients. Smit MD, Van Dessel PF, Rienstra M, Nieuwland W, Wiesfeld AC, Tan ES, Anthonio RL, Van Veldhuisen DJ, Van Gelder IC. Europace. 2006 Aug;8(8):566-72.

Right atrial overdrive pacing for prevention of symptomatic refractory atrial fibrillation. Hemels ME, Wiesfeld AC, Inberg B, Van Dessel PF, Nieuwland W, Tan ES, Mulder H, Van Veldhuisen DJ, Van Gelder IC. Europace. 2006 Feb;8(2):107-12. Epub 2006 Jan 5.

Functional characteristics of coronary vasomotor function following intramyocardial gene therapy with naked DNA encoding for vascular endothelial growth factor165. Tio RA, Wijpkema JS, Tan ES, Asselbergs FW, Hospers GA, Jessurun GA, Zijlstra F. Endothelium. 2005 May-Jun;12(3):103-6.

Radiofrequency ablation of atrial fibrillation. Wiesfeld AC, Tan ES, Van Veldhuisen DJ, Crijns HJ, Van Gelder IC. Int J Cardiol. 2004 Feb;93(2-3):231-7.

PET for evaluation of differential myocardial perfusion dynamics after VEGF gene therapy and laser therapy in end-stage coronary artery disease. Tio RA, Tan ES, Jessurun GA, Veeger N, Jager PL, Slart RH, de Jong RM, Pruim J, Hospers GA, Willemsen AT, de Jongste MJ, van Boven AJ, van Veldhuisen DJ, Zijlstra F. J Nucl Med. 2004 Sep;45(9):1437-43.

Safety evaluation of routine intracoronary acetylcholine infusion in patients undergoing a first diagnostic coronary angiogram. Tio RA, Monnink SH, Amoroso G, Jessurun GA, Veeger N, Volkers C, Hautvast R, Tan ES, van Gilst WH, van Boven AJ. J Investig Med. 2002 Mar;50(2):133-9.

A controlled study of catheter-based myocardial laser revascularization evaluated by positron emission tomography (PET) measurement of myocardial perfusion. abstract. TanE.S, de Jong R, Tio RA, Blanksma PK, van Boven AJ, Crijns HJGM. American Heart, Santa Fe, januari 2001.

Worse clinical outcome but similar graft patency in women versus men one year after coronary artery bypass graft surgery owing to an excess of exposed risk factors in women. CABADAS. Tan ES, van der Meer J, de Kam PJ, Dunselman PH, Mulder BJ, Ascoop CA, Pfisterer M, Lie KI. J Am Coll Cardiol. 1999 Nov 15;34(6):1760-8.

Coronary microcirculation disorders in idiopathic ventricular fibrillation . JG Meeder, PBF Mensink, HJGM Crijns, ES Tan, PK Blanksma, J Pruim, EE van der Wall, W Vaalburg, KI Lie. Journal of Nuclear Cardiology 01/1997; 4(1). DOI:10.1016/S1071-3581(97)91387-8 ·

Comparison of myocardial uptake of fluorine-18-fluorodeoxyglucose imaged with PET and SPECT in dyssynergic myocardium. Bax JJ, Visser FC, Blasnksma PK, Veening MA, Tan ES, Willemsen ATM, van Lingen A, Teule GJ, Vaalburg W, Lie KI, Visser CA. J Nucl Med. 1996 Oct;37(10):1631-6.

Comparison between positron emission tomography myocardial perfusion imaging and intracoronary Doppler flow velocity measurements at rest and during cold pressor testing in angiographically normal coronary arteries in patients with one-vessel coronary artery disease. Meeder JG, Peels HO, Blanksma PK, Tan ES, Pruim J, van der Wall EE, Vaalburg W, Lie KI. Am J Cardiol 1996 Sep 1;78(5):526-31.

Positron Emission Tomography assessment of myocardial viability. In: Cardiac Positron Emission Tomography: Viability, perfusion, receptors, and cardiomyopathy. Tan ES, Eds: van de Wall EE, Blanksma PK, Niemeyer MG, Paans AMJ, Kluwer Academic publishers 1995, ISBN, 0-7923-3472-8, p 25-35.

Is focal myocardial ischemia the cause of angina pectoris in Syndrome X? Joan G. Meeder, Rutger L. Anthonio, Eng S. Tan, Paul K. Blanksma, Jan Pruim, Willem Vaalburg, Kong I Lie. Journal of Nuclear Cardiology 03/1995; 2(2). DOI:10.1016/S1071-3581(05)80562-8 ·

Assessments of coronary endothelial function: Comparison between PET-perfusion and coronary doppler-flow velocity techniques . Joan G. Meeder, Hans-Otto Peels, Eng S. Tan, Paul K. Blanksma, Jan Pruim, Willem Vaalburg, Kong I Lie. Journal of Nuclear Cardiology 03/1995; 2(2):S7. DOI:10.1016/S1071-3581(05)80114

Carbon monoxide poisoning as a trigger for myocardial infarction.Tan ES, van Veldhuisen DJ, Lie KI. Ned Tijdschr Geneeskd. 1993 Oct 30;137(44):2266-8. Dutch.